Field Notes · July 7, 2026 · 6 min · By Hector Lindelof
How to prepare for Mohs surgery: medications, questions, and the week before
Almost nothing about Mohs prep is dramatic, but a short checklist in the week before makes the day itself markedly easier.
Preparing for Mohs surgery is refreshingly undramatic: no fasting, no hospital gown, no anesthesiologist. Because the procedure runs on local numbing, most of the useful preparation is logistical, a handful of medication questions, a few phone calls, and a realistic plan for a long day. Handled in the week before, these small steps remove nearly all of the avoidable friction from an appointment that is already long by design, as the stage-by-stage rhythm in what to expect on the day of Mohs surgery makes clear.
Medications: ask, do not decide alone. The single most important rule is to keep taking prescribed blood thinners unless the doctor who prescribed them says otherwise. Stopping a medically necessary anticoagulant before skin surgery carries real risks of stroke or clot that outweigh the nuisance of extra bruising, and Mohs surgeons manage anticoagulated patients routinely (American College of Mohs Surgery). What you can do is trim the optional extras: casual aspirin or ibuprofen taken for aches, plus supplements like fish oil, vitamin E, garlic, and ginkgo, all promote bleeding and are usually paused about a week out, with your surgeon's confirmation. Bring a complete written list of everything you take, including doses, to the appointment.
Tell the office about hardware and health history. A pacemaker or implanted defibrillator matters because the electrical instrument used to seal small vessels may need adjusting around it. A history of artificial joints or heart valves is worth mentioning in case your other doctors want a precaution, and conditions like diabetes or immune suppression shape wound-care advice. None of these are obstacles; they are simply details the team wants before, not during, the procedure (American Academy of Dermatology).
The 48 hours before. Skip alcohol for two days beforehand, since it thins the blood and worsens oozing. Smokers who cut down or pause even briefly around surgery measurably improve their healing, and the weeks after Mohs are a genuinely useful deadline for a longer attempt. Sleep normally, shower the morning of, and skip makeup, lotion, or aftershave on the surgical site. Eat a full breakfast, take your usual medications with water unless instructed otherwise, and pack the waiting-room kit: a book, a charger, a snack, a sweater, and any midday medications.
Plan the day, then underplan the week. Clear the whole day rather than the morning; the honest math on stages and waiting is covered in how long Mohs surgery takes. Most patients drive themselves home, but arrange a ride if the tumor sits near an eye or you expect to take a relaxing medication. Then look at the week after: desk work usually resumes within a day or two, while lifting and workouts wait longer, so shift anything strenuous now rather than canceling it later.
Questions worth settling in advance. A short call to the office settles the practical unknowns: whether to pause any specific medication, what dressing you will leave with and what supplies to have at home, and whether the likely repair would change the week's plans. A parallel call to your insurer, with the guidance in what Mohs surgery costs, and what insurance covers, removes the financial surprises. And if needle anxiety or procedure dread is the real obstacle, say so when booking; the comfort options described in is Mohs surgery painful work best when arranged ahead (Mayo Clinic on Mohs surgery).
The theme running through all of it is that Mohs preparation is about communication, not endurance. Tell the team what you take and what you have, protect the repair's first week on your calendar, and bring something to read. The procedure supplies the precision; the patient's job is mostly to arrive unhurried.
Related reading: Driving, work, and exercise: returning to normal life after Mohs.
